Modulation of Proteasomal Activity Required for the Generation of a Cytotoxic T Lymphocyte–defined Peptide Derived from the Tumor Antigen MAGE-3

We have analyzed the presentation of human histocompatability leukocyte antigen-A*0201–associated tumor peptide antigen MAGE-3(271–279) by melanoma cells. We show that specific cytotoxic T lymphocyte (CTL)-recognizing cells transfected with a minigene encoding the preprocessed fragment MAGE-3(271–27...

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Bibliographic Details
Main Authors: Valmori, Danila, Gileadi, Uzi, Servis, Catherine, Dunbar, P. Rod, Cerottini, Jean-Charles, Romero, Pedro, Cerundolo, Vincenzo, Lévy, Frédéric
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 1999
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193049/
https://ncbi.nlm.nih.gov/pubmed/10075973
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