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Ex Vivo Staining of Metastatic Lymph Nodes by Class I Major Histocompatibility Complex Tetramers Reveals High Numbers of Antigen-experienced Tumor-specific Cytolytic T Lymphocytes
Characterization of cytolytic T lymphocyte (CTL) responses to tumor antigens has been impeded by a lack of direct assays of CTL activity. We have synthesized reagents (“tetramers”) that specifically stain CTLs recognizing melanoma antigens. Tetramer staining of tumor-infiltrated lymph nodes ex vivo...
Tallennettuna:
Päätekijät: | , , , , , , , , , |
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Aineistotyyppi: | Artigo |
Kieli: | Inglês |
Julkaistu: |
The Rockefeller University Press
1998
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Aiheet: | |
Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2212507/ https://ncbi.nlm.nih.gov/pubmed/9802976 |
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