The Natural Killer T (NKT) Cell Ligand α-Galactosylceramide Demonstrates Its Immunopotentiating Effect by Inducing Interleukin (IL)-12 Production by Dendritic Cells and IL-12 Receptor Expression on NKT Cells

The natural killer T (NKT) cell ligand α-galactosylceramide (α-GalCer) exhibits profound antitumor activities in vivo that resemble interleukin (IL)-12–mediated antitumor activities. Because of these similarities between the activities of α-GalCer and IL-12, we investigated the involvement of IL-12...

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Main Authors: Kitamura, Hidemitsu, Iwakabe, Kenji, Yahata, Takashi, Nishimura, Shin-ichiro, Ohta, Akio, Ohmi, Yasushi, Sato, Marimo, Takeda, Kazuyoshi, Okumura, Ko, Van Kaer, Luc, Kawano, Tetsu, Taniguchi, Masaru, Nishimura, Takashi
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 1999
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193012/
https://ncbi.nlm.nih.gov/pubmed/10190903
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