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Activation or anergy: NKT cells are stunned by α-galactosylceramide

Invariant natural killer T (iNKT) cells are T lymphocytes that behave similarly to cells of the innate immune system. The glycolipid α-galactosylceramide (α-GalCer) is a potent and specific activator of mouse and human iNKT cells and has been used in cancer clinical trials to drive NKT cell–mediated...

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Autori principali: Sullivan, Barbara A., Kronenberg, Mitchell
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1193891/
https://ncbi.nlm.nih.gov/pubmed/16138189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI26297
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