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Activation or anergy: NKT cells are stunned by α-galactosylceramide
Invariant natural killer T (iNKT) cells are T lymphocytes that behave similarly to cells of the innate immune system. The glycolipid α-galactosylceramide (α-GalCer) is a potent and specific activator of mouse and human iNKT cells and has been used in cancer clinical trials to drive NKT cell–mediated...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2005
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1193891/ https://ncbi.nlm.nih.gov/pubmed/16138189 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI26297 |
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