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Mechanisms of NKT cell anergy induction involve Cbl-b-promoted monoubiquitination of CARMA1
Repeated injection of α-galactosylceramide, an agonistic ligand for natural killer T (NKT) cells, results in long-term unresponsiveness or anergy, which severely limits its clinical application. However, the molecular mechanisms leading to NKT anergy induction remain unclear. We show here that the d...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
2009
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2764888/ https://ncbi.nlm.nih.gov/pubmed/19815501 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0904078106 |
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