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Positive and Negative Regulation of  V(D)J Recombination by the E2A Proteins

A key feature of B and T lymphocyte development is the generation of antigen receptors through the rearrangement and assembly of the germline variable (V), diversity (D), and joining (J) gene segments. However, the mechanisms responsible for regulating developmentally ordered gene rearrangements are...

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Detalhes bibliográficos
Main Authors: Bain, Gretchen, Romanow, William J., Albers, Karen, Havran, Wendy L., Murre, Cornelis
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2192990/
https://ncbi.nlm.nih.gov/pubmed/9892611
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