Localized Gene-Specific Induction of Accessibility to V(D)j Recombination Induced by E2a and Early B Cell Factor in Nonlymphoid Cells

Accessibility of immunoglobulin (Ig) gene segments to V(D)J recombination is highly regulated and is normally only achieved in B cell precursors. We previously showed that ectopic expression of E2A or early B cell factor (EBF) with recombination activating gene (RAG) induces rearrangement of IgH and...

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Main Authors: Goebel, Peter, Janney, Noel, Valenzuela, Joaquín R., Romanow, William J., Murre, Cornelis, Feeney, Ann J.
格式: Artigo
語言:Inglês
出版: The Rockefeller University Press 2001
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Original Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2195934/
https://ncbi.nlm.nih.gov/pubmed/11535632
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