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Endotoxin-tolerant Mice Have Mutations in Toll-like Receptor 4 (Tlr4)

Bacterial lipopolysaccharide (LPS) provokes a vigorous, generalized proinflammatory state in the infected host. Genetic regulation of this response has been localized to the Lps locus on mouse chromosome 4, through study of the C3H/HeJ and C57BL/10ScCr inbred strains. Both C3H/HeJ and C57BL/10ScCr m...

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Detalhes bibliográficos
Main Authors: Qureshi, Salman T., Larivière, Line, Leveque, Gary, Clermont, Sophie, Moore, Karen J., Gros, Philippe, Malo, Danielle
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2192941/
https://ncbi.nlm.nih.gov/pubmed/9989976
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