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The cytoplasmic domain of CD4 promotes the development of CD4 lineage T cells

Thymocytes must bind major histocompatibility complex (MHC) proteins on thymic epithelial cells in order to mature into either CD8+ cytotoxic T cells or CD4+ helper T cells. Thymic precursors express both CD8 and CD4, and it has been suggested that the intracellular signals generated by CD8 or CD4 b...

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Bibliografische gegevens
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Rockefeller University Press 1996
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2192343/
https://ncbi.nlm.nih.gov/pubmed/8642277
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