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T-B cell interaction inhibits spontaneous apoptosis of mature lymphocytes in Bcl-2-deficient mice

Bcl-2 expression is tightly regulated during lymphocyte development. Mature lymphocytes in Bcl-2-deficient mice show accelerated spontaneous apoptosis in vivo and in vitro. Stimulation of Bcl-2-deficient lymphocytes by anti-CD3 antibody inhibited the spontaneous apoptosis not only in T cells but als...

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Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 1995
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2192300/
https://ncbi.nlm.nih.gov/pubmed/7561683
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