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Direct association of pp125FAK with paxillin, the focal adhesion- targeting mechanism of pp125FAK

Focal adhesion kinase (pp125FAK) is localized to focal adhesions and tyrosine phosphorylated by the engagement of beta 1 integrins. However, it is unclear how pp125FAK is linked to integrin molecules. We demonstrate that pp125FAK is directly associated with paxillin, a 68-kD cytoskeleton protein. Th...

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Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 1995
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2192281/
https://ncbi.nlm.nih.gov/pubmed/7561682
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