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CD28-B7 blockade after alloantigenic challenge in vivo inhibits Th1 cytokines but spares Th2
Blocking the CD28-B7 T cell costimulatory pathway with the fusion protein CTLA4Ig inhibits alloimmune responses in vitro and in vivo and induces tolerance to cardiac allografts in mice and rats, but the mechanisms mediating the tolerant state in vivo are unknown. Here, we report the effects and pote...
保存先:
| フォーマット: | Artigo |
|---|---|
| 言語: | Inglês |
| 出版事項: |
The Rockefeller University Press
1995
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2192009/ https://ncbi.nlm.nih.gov/pubmed/7536798 |
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