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The role of CD154-CD40 versus CD28-B7 costimulatory pathways in regulating allogeneic Th1 and Th2 responses in vivo

We used signal transducer and activator of transcription 4 (STAT4) and STAT6 gene knockout (–/–) mice as recipients of fully mismatched cardiac allografts to study the role of T-cell costimulatory pathways in regulating allogeneic T-helper 1 (Th1) versus Th2 responses in vivo. STAT4(–/–) mice have i...

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Detalhes bibliográficos
Main Authors: Kishimoto, Koji, Dong, Victor M., Issazadeh, Shohreh, Fedoseyeva, Eugenia V., Waaga, Ana Maria, Yamada, Akira, Sho, Masayuki, Benichou, Gilles, Auchincloss, Hugh, Grusby, Michael J., Khoury, Samia J., Sayegh, Mohamed H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC314364/
https://ncbi.nlm.nih.gov/pubmed/10880049
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