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Greatly reduced lymphoproliferation in lpr mice lacking major histocompatibility complex class I
Mice homozygous for the lpr gene have a defect in fas (CD95), a cell surface receptor that belongs to the tumor necrosis factor receptor family and that mediates apoptosis. This genetic abnormality results in lymphoproliferation characterized by the accumulation of CD4-CD8- (double negative [DN]) T...
Tallennettuna:
| Aineistotyyppi: | Artigo |
|---|---|
| Kieli: | Inglês |
| Julkaistu: |
The Rockefeller University Press
1995
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2191859/ https://ncbi.nlm.nih.gov/pubmed/7530760 |
| Tagit: |
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