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Characterization of an interleukin 4 (IL-4) responsive region in the immunoglobulin heavy chain germline epsilon promoter: regulation by NF- IL-4, a C/EBP family member and NF-kappa B/p50

A large body of data indicate that antibody class switching is directed by cytokines by inducing or repressing transcription from unrearranged, or germline, CH genes. Interleukin 4 (IL-4) induces transcription of the germline C epsilon genes in activated B cells and subsequently, cells in this popul...

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Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 1995
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2191820/
https://ncbi.nlm.nih.gov/pubmed/7807002
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