Heat shock protein 90 mediates macrophage activation by Taxol and bacterial lipopolysaccharide

Taxol, a plant-derived antitumor agent, stabilizes microtubules. Taxol also elicits cell signals in a manner indistinguishable from bacterial lipopolysaccharide (LPS). LPS-like actions of Taxol are controlled by the lps gene and are independent of binding to the known Taxol target, β-tubulin. Using...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Byrd, Cynthia A., Bornmann, William, Erdjument-Bromage, Hediye, Tempst, Paul, Pavletich, Nikola, Rosen, Neal, Nathan, Carl F., Ding, Aihao
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The National Academy of Sciences 1999
Aiheet:
Biological Sciences
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC21914/
https://ncbi.nlm.nih.gov/pubmed/10318938
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