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A major costimulatory molecule on antigen-presenting cells, CTLA4 ligand A, is distinct from B7

CTLA4 ligands are important costimulatory molecules because soluble CTLA4Ig blocks the induction of T cell responses and induces T cell tolerance. As CTLA4 immunoglobulin (CTLA4Ig) binds B7 when the latter is expressed on fibroblasts, it was widely assumed that CTLA4Ig blocks T cell costimulation by...

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Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 1993
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2191247/
https://ncbi.nlm.nih.gov/pubmed/8228824
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