Human alveolar macrophages present antigen ineffectively due to defective expression of B7 costimulatory cell surface molecules.

Alveolar macrophages, resident phagocytic cells in the lung that derive from peripheral blood monocytes, are paradoxically ineffective in presenting antigen to T cells. We found that antigen presentation by alveolar macrophages could be restored by the addition of anti-CD28 mAb to cultures of T cell...

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Bibliographic Details
Main Authors:	Chelen, C J, Fang, Y, Freeman, G J, Secrist, H, Marshall, J D, Hwang, P T, Frankel, L R, DeKruyff, R H, Umetsu, D T
Format:	Artigo
Language:	Inglês
Published:	1995
Subjects:	Research Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC441485/ https://ncbi.nlm.nih.gov/pubmed/7533793
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Human alveolar macrophages present antigen ineffectively due to defective expression of B7 costimulatory cell surface molecules.

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