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The defect in Fas mRNA expression in MRL/lpr mice is associated with insertion of the retrotransposon, ETn

Fas is a cell surface protein of the tumor necrosis factor receptor, nerve growth factor receptor, CD40 family, and is involved in the control of lymphocyte apoptosis. A mutation in the Fas gene in MRL/lpr mice results in massive lymphoproliferation (lpr) and accelerated autoimmunity. To further stu...

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Bibliografski detalji
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 1993
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2191101/
https://ncbi.nlm.nih.gov/pubmed/7688033
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