טוען...
Thalidomide exerts its inhibitory action on tumor necrosis factor alpha by enhancing mRNA degradation
We have examined the mechanism of thalidomide inhibition of lipopolysaccharide (LPS)-induced tumor necrosis factor alpha (TNF- alpha) production and found that the drug enhances the degradation of TNF-alpha mRNA. Thus, the half-life of the molecule was reduced from approximately 30 to approximately...
שמור ב:
| פורמט: | Artigo |
|---|---|
| שפה: | Inglês |
| יצא לאור: |
The Rockefeller University Press
1993
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2191046/ https://ncbi.nlm.nih.gov/pubmed/8496685 |
| תגים: |
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