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Regulation of thymocyte development through CD3. I. Timepoint of ligation of CD3 epsilon determines clonal deletion or induction of developmental program

Several recent observations suggest that successful rearrangement of the T cell receptor (TCR) beta locus induces several important events in thymocyte maturation. Allelic exclusion is achieved by interruption of further rearrangement of the beta locus, and CD4-8- interleukin (IL)- 2R+ cells enter t...

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Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 1993
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2190948/
https://ncbi.nlm.nih.gov/pubmed/8382254
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