Progestin-Inflammatory Cytokine Interactions Affect Matrix Metalloproteinase-1 and -3 Expression in Term Decidual Cells: Implications for Treatment of Chorioamnionitis-Induced Preterm Delivery

Context: Chorioamnionitis (CAM)-elicited preterm delivery (PTD) is associated with elevated amniotic fluid levels of IL-1β and TNF-α. We hypothesized that IL-1β and TNF-α may induce matrix metalloproteinase (MMP)-1 and MMP-3 activity to promote PTD by degrading decidual and fetal membranes and cervi...

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Autors principals: Oner, Ceyda, Schatz, Frederick, Kizilay, Gulnur, Murk, William, Buchwalder, Lynn F., Kayisli, Umit A., Arici, Aydin, Lockwood, Charles J.
Format: Artigo
Idioma:Inglês
Publicat: The Endocrine Society 2008
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2190749/
https://ncbi.nlm.nih.gov/pubmed/17940116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2007-1538
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