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PI3K/AKT inhibition induces caspase-dependent apoptosis in HTLV-1 transformed cells
The phosphatidylinositol-3-kinase (PI3K) and AKT (Protein Kinase B) signaling pathways play an important role in regulating cell cycle progression and cell survival. In previous studies, we demonstrated that AKT is activated in HTLV-1 transformed cells and that Tax activation of AKT is linked to p53...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2007
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2189985/ https://ncbi.nlm.nih.gov/pubmed/17931677 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2007.09.003 |
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