Cortactin Localization to Sites of Actin Assembly in Lamellipodia Requires Interactions with F-Actin and the Arp2/3 Complex

Cortactin is an actin-binding protein that is enriched within the lamellipodia of motile cells and in neuronal growth cones. Here, we report that cortactin is localized with the actin-related protein (Arp) 2/3 complex at sites of actin polymerization within the lamellipodia. Two distinct sequence mo...

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Bibliographic Details
Main Authors: Weed, Scott A., Karginov, Andrei V., Schafer, Dorothy A., Weaver, Alissa M., Kinley, Andrew W., Cooper, John A., Parsons, J. Thomas
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2000
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2189811/
https://ncbi.nlm.nih.gov/pubmed/11018051
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