Significance of Tumor-Associated Stroma in Promotion of Intratumoral Lymphangiogenesis : Pivotal Role of a Hyaluronan-Rich Tumor Microenvironment

Stromal cells, together with extracellular matrix components, provide a tumor microenvironment that is pivotal for cancer cell growth and progression. In our previous study using a conditional transgenic mouse model of breast cancer, the overproduction of hyaluronan, a major extracellular constituen...

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Detalhes bibliográficos
Main Authors: Koyama, Hiroshi, Kobayashi, Nobutaka, Harada, Michihiko, Takeoka, Michiko, Kawai, Yoshiko, Sano, Kenji, Fujimori, Minoru, Amano, Jun, Ohhashi, Toshio, Kannagi, Reiji, Kimata, Koji, Taniguchi, Shun’ichiro, Itano, Naoki
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2008
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2189609/
https://ncbi.nlm.nih.gov/pubmed/18079437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2008.070360
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