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Intratumoral Delivery of Paclitaxel in Solid Tumor from Biodegradable Hyaluronan Nanoparticle Formulations

In the current study, novel paclitaxel-loaded cross-linked hyaluronan nanoparticles were engineered for the local delivery of paclitaxel as a prototype drug for cancer therapy. The nanoparticles were prepared using a desolvation method with polymer cross-linking. In vitro cytotoxicity studies demons...

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Detalhes bibliográficos
Main Authors: Al-Ghananeem, Abeer M., Malkawi, Ahmad H., Muammer, Yahya M., Balko, Justin M., Black, Esther P., Mourad, Walid, Romond, Edward
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2690785/
https://ncbi.nlm.nih.gov/pubmed/19381833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-009-9222-5
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