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Development and evaluation of a novel biodegradable sustained release microsphere formulation of paclitaxel intended to treat breast cancer

OBJECTIVE: The objective of this study was to develop a novel 1 month depot paclitaxel (PTX) microspheres that give a sustained and complete drug release. MATERIALS AND METHODS: PTX loaded microspheres were prepared by o/w emulsion solvent evaporation technique using the blends of poly(lactic-co-gly...

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Détails bibliographiques
Auteurs principaux: Shiny, Jacob, Ramchander, Thadkapally, Goverdhan, Puchchakayala, Habibuddin, Mohammad, Aukunuru, Jithan Venkata
Format: Artigo
Langue:Inglês
Publié: Medknow Publications & Media Pvt Ltd 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3807978/
https://ncbi.nlm.nih.gov/pubmed/24167783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/2230-973X.119212
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