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Preferential inhibition of plasmid replication in vivo by altered DNA gyrase activity in Escherichia coli.

The thermosensitive growth phenotype exerted by runaway-mutant plasmids was suppressed by sublethal doses of the DNA gyrase inhibitors novobiocin or nalidixic acid, although the latter drug was less efficient. A novobiocin-resistant gyrB mutant Escherichia coli strain prevented expression of the run...

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Pubblicato in:J Bacteriol
Autori principali: Uhlin, B E, Nordström, K
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 1985
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC218936/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2985550/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.162.2.855-857.1985
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