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Role of CD4 in thymocyte selection and maturation

We examined the possible role of CD4 molecules during in vivo and in vitro fetal thymic development. Our results show that fetal thymi treated with intact anti-CD4 mAbs fail to generate CD4 single-positive T cells, while the generation of the other phenotypes remains unchanged. Most importantly, the...

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Bibliographic Details
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 1989
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2189331/
https://ncbi.nlm.nih.gov/pubmed/2525172
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