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Autocrine growth and tumorigenicity of interleukin 2-dependent helper T cells transfected with IL-2 gene
We introduced a mouse IL-2 cDNA expression vector into an IL-2- dependent mouse helper T cell line HT-2. Transfected cells secreted substantial amounts of IL-2, to which they themselves responded by proliferating without further requirement for exogenous IL-2. The proliferation was a direct function...
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| Format: | Artigo |
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| Sprog: | Inglês |
| Udgivet: |
The Rockefeller University Press
1989
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2189182/ https://ncbi.nlm.nih.gov/pubmed/2521241 |
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