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Growth autonomy and tumorigenicity of interleukin 6-dependent B cells transfected with interleukin 6 cDNA

We introduced an IL-6 cDNA expression vector into a murine B cell line, the growth of which definitely required the presence of exogenous IL-6. The transfected cells secreted substantial amounts of IL-6, to which they themselves responded by proliferating without further requirement of exogenous IL-...

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Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 1990
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2187732/
https://ncbi.nlm.nih.gov/pubmed/2303779
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