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Continuing rearrangement but absence of somatic hypermutation in immunoglobulin genes of human B cell precursor leukemia

Southern blot analyses revealed that cells from nearly 30% of childhood B cell precursor acute lymphoblastic leukemias (ALLs) contained more than two rearranged, nongermline bands for Ig heavy chain genes. DNA corresponding to these bands was molecularly cloned from two cases which showed three and...

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Bibliographic Details
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 1988
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2188972/
https://ncbi.nlm.nih.gov/pubmed/2840480
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