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Downregulation of tumor necrosis factor (TNF) sensitivity via modulation of TNF binding capacity by protein kinase C activators

The regulatory action of activators for protein kinase C on the specific binding capacity for recombinant human tumor necrosis factor alpha (TNF-alpha) was studied on various human cell lines. Phorbol myristate acetate (PMA) and oleyl acetyl glycerol (OAG) both are able to rapidly downregulate TNF-b...

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Bibliographic Details
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 1987
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2188787/
https://ncbi.nlm.nih.gov/pubmed/2824656
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