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E1A Sensitizes Cells to Tumor Necrosis Factor Alpha by Downregulating c-FLIP(S)
Tumor necrosis factor alpha (TNF-α) activates both apoptosis and NF-κB-dependent survival pathways, the former of which requires inhibition of gene expression to be manifested. c-FLIP is a TNF-α-induced gene that inhibits caspase-8 activation during TNF-α signaling. Adenovirus infection and E1A expr...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC141118/ https://ncbi.nlm.nih.gov/pubmed/12552004 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.4.2651-2662.2003 |
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