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Coding sequences of the tal-1 gene are disrupted by chromosome translocation in human T cell leukemia

The tal-1 proto-oncogene encodes a helix-loop-helix DNA-binding protein that has been implicated in the formation of T cell acute lymphoblastic leukemia (T-ALL). Patients with T-ALL harbor structural rearrangements of tal-1 that result from either local DNA deletion or t(1;14)(p34;q11) chromosome tr...

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Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 1990
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2188666/
https://ncbi.nlm.nih.gov/pubmed/2230650
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