NKX3.1 is a direct TAL1 target gene that mediates proliferation of TAL1-expressing human T cell acute lymphoblastic leukemia

TAL1 (also known as SCL) is expressed in >40% of human T cell acute lymphoblastic leukemias (T-ALLs). TAL1 encodes a basic helix-loop-helix transcription factor that can interfere with the transcriptional activity of E2A and HEB during T cell leukemogenesis; however, the oncogenic pathways direct...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Kusy, Sophie, Gerby, Bastien, Goardon, Nicolas, Gault, Nathalie, Ferri, Federica, Gérard, Delphine, Armstrong, Florence, Ballerini, Paola, Cayuela, Jean-Michel, Baruchel, André, Pflumio, Françoise, Roméo, Paul-Henri
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2010
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2947082/
https://ncbi.nlm.nih.gov/pubmed/20855495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20100745
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados