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Structure and expression of germline epsilon transcripts in human B cells induced by interleukin 4 to switch to IgE production

Interleukin 4 (IL-4)-induced IgE production coincides with the appearance of the 2.2-kb productive epsilon-mRNA, but is preceded by synthesis of a 1.7-kb epsilon-RNA. Analysis of cDNA copies of the 5' end of this RNA indicated that the 1.7-kb epsilon-RNA is a germline epsilon immunoglobulin hea...

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Format: Artigo
Langue:Inglês
Publié: The Rockefeller University Press 1990
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2188335/
https://ncbi.nlm.nih.gov/pubmed/1695667
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