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Interleukin 4 induces changes in the chromatin structure of the gamma 1 switch region in resting B cells before switch recombination

Interleukin 4 (IL-4) can induce the expression of IgG1 in sIgG- murine B cells stimulated with mitogens or through a cognate interaction with T helper (Th) cells. We have investigated the molecular basis for the IL-4-induced switch to IgG1 in lipopolysaccharide (LPS)-stimulated murine B cells and ha...

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Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 1990
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2188184/
https://ncbi.nlm.nih.gov/pubmed/2358783
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