A carregar...
The action of leucyl-leucine methyl ester on cytotoxic lymphocytes requires uptake by a novel dipeptide-specific facilitated transport system and dipeptidyl peptidase I-mediated conversion to membranolytic products
The mechanism of toxicity for cytolytic lymphocytes of Leu-Leu-OMe and related dipeptide derivatives was examined. Selective inhibition of dipeptidyl peptidase I (DPPI), a lysosomal thiol protease highly enriched in cytotoxic lymphocytes, prevented all natural killer (NK) toxic effects of such agent...
Na minha lista:
| Formato: | Artigo |
|---|---|
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
1990
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2188150/ https://ncbi.nlm.nih.gov/pubmed/1972727 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|