Soluble CD40 ligand induces β(3) integrin tyrosine phosphorylation and triggers platelet activation by outside-in signaling

We earlier reported that the soluble form of the CD40 ligand (sCD40L), is involved in thrombosis by stabilizing platelet thrombi. In this article, we have determined the mechanism by which this protein affects platelet biology. Addition of sCD40L to washed platelets was found to activate the recepto...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Prasad, K. S. Srinivasa, Andre, Patrick, He, Ming, Bao, Ming, Manganello, Jeanne, Phillips, David R.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 2003
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC218764/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14519852/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.2032886100
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