Soluble CD40 ligand induces β(3) integrin tyrosine phosphorylation and triggers platelet activation by outside-in signaling

We earlier reported that the soluble form of the CD40 ligand (sCD40L), is involved in thrombosis by stabilizing platelet thrombi. In this article, we have determined the mechanism by which this protein affects platelet biology. Addition of sCD40L to washed platelets was found to activate the recepto...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Prasad, K. S. Srinivasa, Andre, Patrick, He, Ming, Bao, Ming, Manganello, Jeanne, Phillips, David R.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 2003
Soggetti:	Biological Sciences
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC218764/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14519852/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.2032886100
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