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Soluble CD40 ligand induces β(3) integrin tyrosine phosphorylation and triggers platelet activation by outside-in signaling
We earlier reported that the soluble form of the CD40 ligand (sCD40L), is involved in thrombosis by stabilizing platelet thrombi. In this article, we have determined the mechanism by which this protein affects platelet biology. Addition of sCD40L to washed platelets was found to activate the recepto...
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| Main Authors: | , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
National Academy of Sciences
2003
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC218764/ https://ncbi.nlm.nih.gov/pubmed/14519852 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2032886100 |
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