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Stimulation of lymphokine release from T lymphoblasts. Requirement for mRNA synthesis and inhibition by cyclosporin A

Three-day, concanavalin A-induced T lymphoblasts have been used as a model to study lymphokine release from sensitized T cells. The blasts responded to interleukin 2 (IL-2) but did not constitutively produce this or other lymphokines. After mitogen restimulation, blast cells synthesized IL-2 as well...

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Détails bibliographiques
Format: Artigo
Langue:Inglês
Publié: The Rockefeller University Press 1984
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2187533/
https://ncbi.nlm.nih.gov/pubmed/6334715
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