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Anti-mRNA: specific inhibition of translation of single mRNA molecules.

A plasmid was constructed to generate RNA complementary to the beta-galactosidase mRNA under control of the phage lambda PL promoter. When this anti-mRNA was produced, synthesis of beta-galactosidase was dramatically inhibited (98%). Syntheses of galactoside permease and transacetylase, whose coding...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Pestka, S, Daugherty, B L, Jung, V, Hotta, K, Pestka, R K
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1984
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC392179/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6438637/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.81.23.7525
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