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Stimulation of human endothelial cell prostacyclin synthesis by select leukotrienes

Cultured endothelial cells from human umbilical cord labeled with [3H]20:4 release radiolabel when exposed to leukotrienes C or D (LTC or LTD). The major radiolabeled 20:4 metabolite recovered in the culture medium was prostacyclin. Both leukotrienes produced a dose-dependent synthesis of prostacycl...

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Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 1984
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2187472/
https://ncbi.nlm.nih.gov/pubmed/6148375
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