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Carboxylic ionophores enhance the cytotoxic potency of ligand- and antibody-delivered ricin A chain

The highly selective cytotoxicity of site-directed ricin A chain conjugates can be potentiated by membrane-active carboxylic ionophores. The combined use of the two agents results in much faster inactivation of ribosomes and subsequent cell death and lysis. The potency of A chain cytotoxins is corre...

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Bibliografski detalji
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 1984
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2187464/
https://ncbi.nlm.nih.gov/pubmed/6090575
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