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Gene expression profiling in Werner syndrome closely resembles that of normal aging

Werner syndrome (WS) is a premature aging disorder, displaying defects in DNA replication, recombination, repair, and transcription. It has been hypothesized that several WS phenotypes are secondary consequences of aberrant gene expression and that a transcription defect may be crucial to the develo...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Kyng, Kasper J., May, Alfred, Kølvraa, Steen, Bohr, Vilhelm A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2003
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Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC218746/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14527998/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.2130723100
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