Mechanism of nucleotide incorporation opposite a thymine-thymine dimer by yeast DNA polymerase η
DNA polymerase η (Polη) has the unique ability to replicate through UV-light-induced cyclobutane pyrimidine dimers. Here we use pre-steady-state kinetic analyses to examine the mechanism of nucleotide incorporation opposite a cis-syn thymine-thymine (TT) dimer and an identical nondamaged sequence by...
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| Publié dans: | Proc Natl Acad Sci U S A |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
2003
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC218718/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14527996/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.2134223100 |
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