Mechanism of nucleotide incorporation opposite a thymine-thymine dimer by yeast DNA polymerase η

DNA polymerase η (Polη) has the unique ability to replicate through UV-light-induced cyclobutane pyrimidine dimers. Here we use pre-steady-state kinetic analyses to examine the mechanism of nucleotide incorporation opposite a cis-syn thymine-thymine (TT) dimer and an identical nondamaged sequence by...

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Argitaratua izan da:	Proc Natl Acad Sci U S A
Egile Nagusiak:	Washington, M. Todd, Prakash, Louise, Prakash, Satya
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	National Academy of Sciences 2003
Gaiak:	Biological Sciences
Sarrera elektronikoa:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC218718/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14527996/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.2134223100
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